:root {
    --paper: #f4f4f1;
    --surface: #ffffff;
    --stage: #ecece8;
    --ink: #0a0a0a;
    --muted: #666662;
    --line: rgba(10, 10, 10, .16);
    --line-dark: rgba(255, 255, 255, .2);
    --accent: #e52f66;
    --page-x: clamp(20px, 4.5vw, 76px);
    --content: 1540px;
    --header-h: 94px;
}

* {
    box-sizing: border-box;
}

html {
    scroll-behavior: smooth;
    scroll-padding-top: var(--header-h);
}

body {
    margin: 0;
    background: var(--paper);
    color: var(--ink);
    font-family: -apple-system, BlinkMacSystemFont, "Segoe UI Variable Display", "Segoe UI", Helvetica, Arial, sans-serif;
    -webkit-font-smoothing: antialiased;
    text-rendering: optimizeLegibility;
}

::selection {
    background: rgba(229, 47, 102, .2);
}

a {
    color: inherit;
}

a:focus-visible {
    outline: 2px solid var(--accent);
    outline-offset: 5px;
}

img {
    max-width: 100%;
}

.shell {
    width: min(100%, var(--content));
    margin: 0 auto;
    padding-right: max(var(--page-x), env(safe-area-inset-right));
    padding-left: max(var(--page-x), env(safe-area-inset-left));
}

.skip-link {
    position: fixed;
    z-index: 30;
    top: 12px;
    left: 12px;
    padding: 11px 15px;
    background: var(--ink);
    color: var(--surface);
    font-size: 13px;
    text-decoration: none;
    transform: translateY(-160%);
}

.skip-link:focus {
    transform: translateY(0);
}

.site-header {
    position: fixed;
    z-index: 20;
    top: 0;
    right: 0;
    left: 0;
    background: rgba(244, 244, 241, .88);
    backdrop-filter: blur(20px) saturate(150%);
    -webkit-backdrop-filter: blur(20px) saturate(150%);
}

.site-header__inner {
    position: relative;
    display: flex;
    width: min(100%, var(--content));
    height: var(--header-h);
    margin: 0 auto;
    padding-right: max(var(--page-x), env(safe-area-inset-right));
    padding-left: max(var(--page-x), env(safe-area-inset-left));
    align-items: center;
    justify-content: space-between;
}

.site-header__inner::after {
    position: absolute;
    right: auto;
    bottom: 0;
    left: 50%;
    width: 100vw;
    height: 1px;
    background: var(--line);
    transform: translateX(-50%);
    content: "";
}

.brand {
    display: inline-flex;
    align-items: center;
}

.brand img {
    display: block;
    width: 126px;
    height: auto;
}

.site-nav {
    display: flex;
    align-items: center;
    gap: clamp(22px, 2.7vw, 44px);
    font-size: 13px;
    font-weight: 600;
}

.site-nav a {
    text-decoration: none;
}

.site-nav__link {
    position: relative;
    padding: 10px 0;
}

.site-nav__link::after {
    position: absolute;
    right: 0;
    bottom: 6px;
    left: 0;
    height: 1px;
    background: currentColor;
    content: "";
    transform: scaleX(0);
    transform-origin: right;
    transition: transform .25s ease;
}

.site-nav__link:hover::after {
    transform: scaleX(1);
    transform-origin: left;
}

.site-nav__contacts {
    display: flex;
    align-items: center;
    gap: 8px;
}

.site-nav__contact {
    display: inline-flex;
    min-height: 44px;
    padding: 0 19px;
    border: 1px solid var(--ink);
    border-radius: 3px;
    align-items: center;
    justify-content: center;
    gap: 7px;
    white-space: nowrap;
    transition: background-color .2s ease, color .2s ease;
}

.site-nav__contact span {
    transition: transform .2s ease;
}

.site-nav__contact:hover {
    background: var(--ink);
    color: var(--surface);
}

.site-nav__contact:hover span {
    transform: translate(2px, -1px);
}

.hero {
    padding-top: calc(var(--header-h) + clamp(38px, 4vw, 66px));
    padding-bottom: clamp(72px, 8vw, 122px);
}

.hero__grid {
    display: grid;
    min-height: clamp(650px, calc(100svh - 220px), 790px);
    grid-template-columns: minmax(0, .78fr) minmax(0, 1.22fr);
    gap: clamp(52px, 5vw, 96px);
    align-items: center;
}

.hero__copy,
.product-stage {
    min-width: 0;
}

.hero__copy {
    max-width: 570px;
    animation: intro-copy .65s cubic-bezier(.2, .7, .2, 1) both;
}

h2,
h3,
p {
    overflow-wrap: break-word;
}

h1 {
    margin: 0;
    font-size: clamp(72px, 5.6vw, 102px);
    font-weight: 650;
    hyphens: none;
    letter-spacing: -.07em;
    line-height: .9;
    overflow-wrap: normal;
    white-space: nowrap;
    word-break: normal;
}

.hero__lead {
    max-width: 560px;
    margin: clamp(34px, 3.2vw, 50px) 0 0;
    font-size: clamp(18px, 1.32vw, 21px);
    letter-spacing: -.025em;
    line-height: 1.52;
}

.hero__lead + .hero__lead {
    margin-top: 17px;
}

.contact__actions {
    display: flex;
    align-items: center;
    gap: 10px;
    flex-wrap: wrap;
}

.button {
    display: inline-flex;
    min-height: 54px;
    padding: 0 23px;
    border: 1px solid var(--ink);
    border-radius: 3px;
    align-items: center;
    justify-content: center;
    gap: 12px;
    font-size: 14px;
    font-weight: 650;
    text-decoration: none;
    transition: transform .2s ease, background-color .2s ease, color .2s ease;
}

.button span,
.source-links span {
    transition: transform .2s ease;
}

.button:hover {
    transform: translateY(-2px);
}

.button:hover span,
.source-links a:hover span {
    transform: translate(3px, -2px);
}

.button--primary {
    background: var(--ink);
    color: var(--surface);
}

.button--primary:hover {
    background: #262626;
}

.button--secondary {
    background: transparent;
}

.button--secondary:hover {
    background: var(--surface);
}

.product-stage {
    position: relative;
    height: 100%;
    min-height: 620px;
    margin: 0;
    overflow: hidden;
    background: var(--stage);
    isolation: isolate;
    animation: intro-product .85s .08s cubic-bezier(.2, .7, .2, 1) both;
}

.product-stage::before {
    position: absolute;
    z-index: -1;
    right: 9%;
    bottom: 11%;
    left: 9%;
    height: 15%;
    border-radius: 50%;
    background: radial-gradient(ellipse, rgba(10, 10, 10, .12), rgba(10, 10, 10, 0) 68%);
    filter: blur(18px);
    content: "";
}

.product-stage__kicker {
    position: absolute;
    z-index: 3;
    top: 24px;
    right: 28px;
    left: 28px;
    display: flex;
    margin: 0;
    align-items: center;
    justify-content: space-between;
    gap: 24px;
    color: var(--muted);
    font-family: ui-monospace, "SFMono-Regular", Consolas, monospace;
    font-size: 10px;
    font-weight: 700;
    letter-spacing: .12em;
    text-transform: uppercase;
    white-space: nowrap;
}

.product-stage picture {
    position: absolute;
    inset: 62px -16px 62px;
    display: grid;
    place-items: center;
}

.product-stage img {
    display: block;
    width: 100%;
    height: 100%;
    max-width: none;
    object-fit: contain;
    filter: drop-shadow(0 30px 28px rgba(10, 10, 10, .1));
}

.hero__facts {
    display: grid;
    margin-top: clamp(28px, 3.5vw, 52px);
    border-top: 1px solid var(--line);
    border-bottom: 1px solid var(--line);
    grid-template-columns: repeat(3, minmax(0, 1fr));
}

.hero__facts div {
    min-width: 0;
    padding: 24px clamp(18px, 2vw, 38px) 27px 0;
}

.hero__facts div + div {
    padding-left: clamp(18px, 2.2vw, 36px);
    border-left: 1px solid var(--line);
}

.hero__facts span,
.outcome__label {
    color: var(--muted);
    font-family: ui-monospace, "SFMono-Regular", Consolas, monospace;
    font-size: 9px;
    font-weight: 700;
    letter-spacing: .1em;
    text-transform: uppercase;
}

.hero__facts p {
    margin: 11px 0 0;
    font-size: 15px;
    font-weight: 600;
    letter-spacing: -.015em;
}

.mechanism {
    position: relative;
    overflow: hidden;
    isolation: isolate;
    padding: clamp(104px, 11vw, 174px) 0 clamp(96px, 10vw, 160px);
    background:
        radial-gradient(105% 95% at 0 0, rgba(10, 10, 10, .97) 0%, rgba(10, 10, 10, .83) 48%, rgba(10, 10, 10, .34) 100%),
        linear-gradient(180deg, rgba(10, 10, 10, .995) 0%, rgba(10, 10, 10, .94) 31%, rgba(10, 10, 10, .68) 63%, rgba(10, 10, 10, .46) 100%),
        url("/bimagrumab-assets/mechanism-muscle-hypertrophy-red-v1.png?v=20260901-6") center bottom / cover no-repeat,
        var(--ink);
    color: var(--surface);
}

.section-label {
    display: flex;
    margin: 0 0 clamp(50px, 6vw, 88px);
    align-items: center;
    gap: 13px;
    color: var(--muted);
    font-family: ui-monospace, "SFMono-Regular", Consolas, monospace;
    font-size: 10px;
    font-weight: 700;
    letter-spacing: .11em;
    text-transform: uppercase;
}

.section-label::after {
    height: 1px;
    margin-left: 5px;
    background: var(--line);
    content: "";
    flex: 1;
}

.section-label span {
    color: var(--accent);
}

.mechanism .section-label {
    color: #969692;
}

.mechanism .section-label::after {
    background: var(--line-dark);
}

.mechanism__intro {
    display: grid;
    grid-template-columns: minmax(0, 1.55fr) minmax(300px, .45fr);
    gap: clamp(64px, 9vw, 148px);
    align-items: end;
}

.mechanism__intro,
.mechanism__intro > *,
.potential__body,
.potential__body > *,
.evidence__intro,
.evidence__intro > *,
.contact__body,
.contact__body > * {
    min-width: 0;
}

.mechanism h2,
.evidence h2,
.contact h2 {
    margin: 0;
    font-size: clamp(54px, 6vw, 94px);
    font-weight: 620;
    letter-spacing: -.065em;
    line-height: .96;
}

.mechanism__summary p {
    margin: 0;
    color: #c6c6c1;
    font-size: clamp(17px, 1.35vw, 21px);
    letter-spacing: -.02em;
    line-height: 1.55;
}

.mechanism__summary p + p {
    margin-top: 25px;
    color: #858581;
    font-size: 15px;
}

.mechanism__steps {
    display: grid;
    margin: clamp(80px, 8vw, 126px) 0 0;
    padding: 0;
    border-top: 1px solid var(--line-dark);
    grid-template-columns: repeat(3, minmax(0, 1fr));
    list-style: none;
}

.mechanism__steps li {
    min-width: 0;
    padding: 28px clamp(24px, 3.4vw, 54px) 38px 0;
}

.mechanism__steps li + li {
    padding-left: clamp(24px, 3.4vw, 54px);
    border-left: 1px solid var(--line-dark);
}

.step__number {
    color: var(--accent);
    font-family: ui-monospace, "SFMono-Regular", Consolas, monospace;
    font-size: 10px;
    font-weight: 700;
    letter-spacing: .08em;
}

.mechanism__steps h3 {
    margin: 54px 0 17px;
    font-size: clamp(24px, 2vw, 31px);
    font-weight: 600;
    letter-spacing: -.04em;
}

.mechanism__steps p {
    max-width: 330px;
    margin: 0;
    color: #999995;
    font-size: 15px;
    line-height: 1.55;
}

.pathway {
    display: flex;
    margin-top: clamp(64px, 7vw, 108px);
    padding: 25px 0;
    border-top: 1px solid var(--line-dark);
    border-bottom: 1px solid var(--line-dark);
    align-items: center;
    justify-content: space-between;
    gap: 24px;
    color: #bcbcb7;
    font-family: ui-monospace, "SFMono-Regular", Consolas, monospace;
    font-size: clamp(10px, 1vw, 13px);
    font-weight: 700;
    letter-spacing: .08em;
    text-transform: uppercase;
}

.pathway i {
    color: var(--accent);
    font-family: inherit;
    font-size: 18px;
    font-style: normal;
}

.evidence {
    padding: clamp(104px, 11vw, 174px) 0 clamp(98px, 10vw, 160px);
    background:
        linear-gradient(180deg, rgba(248, 247, 243, .995) 0%, rgba(248, 247, 243, .72) 42%, rgba(248, 247, 243, .08) 66%, rgba(248, 247, 243, 0) 100%),
        linear-gradient(90deg, rgba(248, 247, 243, .998) 0%, rgba(248, 247, 243, .93) 42%, rgba(248, 247, 243, .04) 76%, rgba(248, 247, 243, 0) 100%),
        url("/bimagrumab-assets/evidence-composition-biological-v1.png?v=20260901-2") right bottom / cover no-repeat,
        var(--surface);
}

.evidence__intro {
    display: grid;
    grid-template-columns: minmax(0, 1.2fr) minmax(320px, .8fr);
    gap: clamp(60px, 9vw, 146px);
    align-items: end;
}

.evidence__intro > p {
    max-width: 510px;
    margin: 0;
    color: var(--muted);
    font-size: clamp(18px, 1.45vw, 22px);
    letter-spacing: -.025em;
    line-height: 1.55;
}

.outcomes {
    display: grid;
    margin-top: clamp(76px, 8vw, 124px);
    border-top: 1px solid var(--line);
    border-bottom: 1px solid var(--line);
    grid-template-columns: repeat(2, minmax(0, 1fr));
}

.outcome {
    display: grid;
    min-width: 0;
    padding: clamp(34px, 4vw, 62px) clamp(28px, 4.5vw, 72px) clamp(40px, 5vw, 72px) 0;
    grid-template-columns: auto 1fr;
    gap: clamp(20px, 3vw, 42px);
}

.outcome + .outcome {
    padding-right: 0;
    padding-left: clamp(28px, 4.5vw, 72px);
    border-left: 1px solid var(--line);
}

.outcome__mark {
    color: var(--accent);
    font-family: ui-monospace, "SFMono-Regular", Consolas, monospace;
    font-size: clamp(11px, .9vw, 14px);
    font-weight: 700;
    letter-spacing: .08em;
    line-height: 1;
    text-transform: uppercase;
}

.outcome__label {
    display: block;
    margin: 3px 0 22px;
}

.outcome h3 {
    max-width: 460px;
    margin: 0;
    font-size: clamp(27px, 2.45vw, 38px);
    font-weight: 610;
    letter-spacing: -.045em;
    line-height: 1.08;
}

.outcome div > p:last-child {
    max-width: 440px;
    margin: 28px 0 0;
    color: var(--muted);
    font-size: 15px;
    line-height: 1.55;
}

.potential {
    padding: clamp(80px, 7vw, 118px) 0 clamp(78px, 6.5vw, 108px);
    background: var(--ink);
    color: var(--surface);
}

.potential .section-label {
    color: #969692;
}

.potential .section-label::after {
    background: var(--line-dark);
}

.potential__body {
    display: grid;
    grid-template-columns: minmax(0, 1.25fr) minmax(320px, .75fr);
    gap: clamp(40px, 5vw, 84px);
    align-items: end;
}

.potential h2 {
    max-width: 760px;
    margin: 0;
    font-size: clamp(40px, 3.8vw, 64px);
    font-weight: 620;
    letter-spacing: -.06em;
    line-height: 1.02;
}

.potential__body p {
    max-width: 440px;
    margin: 0;
    color: #c6c6c1;
    font-size: clamp(17px, 1.1vw, 20px);
    letter-spacing: -.025em;
    line-height: 1.55;
}

.evidence__footer {
    display: flex;
    margin-top: 34px;
    align-items: flex-start;
    justify-content: space-between;
    gap: 28px 60px;
}

.evidence__footer > p {
    margin: 0;
    color: var(--muted);
    font-size: 12px;
    line-height: 1.55;
}

.source-links {
    display: flex;
    max-width: 100%;
    margin-left: 0;
    align-self: flex-start;
    justify-content: flex-start;
    gap: 14px 28px;
    flex-wrap: wrap;
    text-align: left;
}

.source-links a {
    display: inline-flex;
    align-items: center;
    gap: 7px;
    color: var(--muted);
    font-size: 12px;
    font-weight: 650;
    text-decoration-line: underline;
    text-decoration-color: rgba(10, 10, 10, .25);
    text-underline-offset: 4px;
}

.source-links a:hover {
    color: var(--ink);
}

.contact {
    position: relative;
    padding: clamp(106px, 11vw, 174px) 0 clamp(112px, 12vw, 188px);
    overflow: hidden;
    background: var(--paper);
    isolation: isolate;
}

.contact .shell {
    position: relative;
    z-index: 1;
}

.contact__signature {
    position: absolute;
    z-index: 0;
    right: -3vw;
    bottom: -38%;
    width: min(44vw, 650px);
    height: auto;
    color: rgba(10, 10, 10, .065);
    pointer-events: none;
    transform: rotate(-16deg);
}

.contact__body {
    display: grid;
    grid-template-columns: minmax(0, 1fr) minmax(440px, .9fr);
    gap: clamp(48px, 6vw, 96px);
    align-items: end;
}

.contact h2 {
    font-size: clamp(54px, 5.2vw, 82px);
}

.contact__aside > p {
    max-width: 460px;
    margin: 0;
    color: var(--muted);
    font-size: clamp(18px, 1.4vw, 21px);
    letter-spacing: -.02em;
    line-height: 1.55;
}

.contact__actions {
    margin-top: 0;
    flex-wrap: nowrap;
}

.contact__aside > p + .contact__actions {
    margin-top: 30px;
}

.contact__actions .button {
    white-space: nowrap;
}

.site-footer {
    border-top: 1px solid var(--line-dark);
    background: var(--ink);
    color: #aaa9a4;
}

.site-footer__inner {
    display: grid;
    min-height: 120px;
    padding-top: 30px;
    padding-bottom: 30px;
    grid-template-columns: 104px minmax(0, 960px) auto;
    align-items: center;
    justify-content: space-between;
    gap: clamp(32px, 5vw, 80px);
}

.site-footer img {
    display: block;
    width: 104px;
    height: auto;
    filter: invert(1);
}

.site-footer__legal {
    max-width: 960px;
    margin: 0;
    color: #aaa9a4;
    font-size: 12px;
    line-height: 1.65;
}

.site-footer__copyright {
    margin: 0;
    font-family: ui-monospace, "SFMono-Regular", Consolas, monospace;
    font-size: 10px;
    letter-spacing: .06em;
    text-align: right;
    text-transform: uppercase;
    white-space: nowrap;
}

@media (max-width: 319px) {
    html,
    body,
    .site-header {
        min-width: 320px;
    }
}

@media (min-width: 1920px) {
    :root {
        --content: clamp(1540px, 70vw, 2160px);
        --page-x: clamp(76px, 3vw, 96px);
        --header-h: clamp(108px, 2.8vw, 124px);
    }

    .brand img {
        width: clamp(126px, 4vw, 156px);
    }

    .site-nav {
        gap: clamp(36px, 2.5vw, 52px);
        font-size: clamp(14px, .42vw, 16px);
    }

    .site-nav__contact {
        min-height: clamp(52px, 1.6vw, 62px);
        padding: 0 clamp(22px, 1.1vw, 30px);
    }

    .hero {
        padding-top: calc(var(--header-h) + clamp(46px, 3.2vw, 78px));
        padding-bottom: clamp(104px, 6vw, 160px);
    }

    .hero__grid {
        min-height: clamp(760px, calc(100svh - 230px), 1080px);
        grid-template-columns: minmax(0, .86fr) minmax(0, 1.14fr);
        gap: clamp(72px, 4vw, 120px);
    }

    .hero__copy {
        max-width: 700px;
    }

    h1 {
        font-size: clamp(102px, 4.5vw, 144px);
    }

    .hero__lead {
        max-width: 640px;
        font-size: clamp(21px, .95vw, 25px);
    }

    .button {
        min-height: clamp(56px, 1.65vw, 62px);
        padding: 0 clamp(23px, 1.2vw, 30px);
        font-size: clamp(14px, .42vw, 16px);
    }

    .product-stage {
        min-height: clamp(720px, 34vw, 960px);
    }

    .product-stage__kicker {
        top: clamp(26px, 1.4vw, 34px);
        right: clamp(30px, 1.6vw, 42px);
        left: clamp(30px, 1.6vw, 42px);
        font-size: clamp(10px, .5vw, 12px);
    }

    .product-stage picture {
        inset: clamp(70px, 3vw, 92px) clamp(10px, .8vw, 20px);
    }

    .hero__facts {
        margin-top: clamp(42px, 3.2vw, 64px);
    }

    .hero__facts div {
        padding-top: clamp(30px, 1.8vw, 38px);
        padding-bottom: clamp(32px, 2vw, 42px);
    }

    .hero__facts span,
    .outcome__label,
    .section-label,
    .step__number {
        font-size: clamp(10px, .5vw, 12px);
    }

    .hero__facts p {
        margin-top: 13px;
        font-size: clamp(17px, .78vw, 20px);
    }

    .hero__facts span {
        font-size: clamp(11px, .5vw, 14px);
    }

    .mechanism,
    .evidence {
        padding-top: clamp(174px, 9vw, 230px);
        padding-bottom: clamp(160px, 8vw, 210px);
    }

    .potential {
        padding-top: clamp(118px, 6vw, 150px);
        padding-bottom: clamp(108px, 5.5vw, 138px);
    }

    .contact {
        padding-top: clamp(174px, 9vw, 230px);
        padding-bottom: clamp(188px, 9vw, 232px);
    }

    .section-label {
        margin-bottom: clamp(76px, 5vw, 104px);
    }

    .mechanism,
    .evidence {
        background-position: center, center, right bottom;
        background-size: 100% 100%, 100% 100%, min(100%, 2160px) auto;
    }

    .mechanism__summary p,
    .evidence__intro > p,
    .contact__aside > p {
        font-size: clamp(21px, 1vw, 24px);
    }

    .potential__body p {
        font-size: clamp(18px, .8vw, 20px);
    }

    .mechanism__summary p + p {
        font-size: clamp(16px, .74vw, 18px);
    }

    .mechanism__steps {
        margin-top: clamp(108px, 6vw, 142px);
    }

    .mechanism__steps li {
        padding-top: clamp(34px, 2vw, 44px);
        padding-bottom: clamp(44px, 2.8vw, 58px);
    }

    .mechanism__steps h3 {
        margin-top: clamp(52px, 3vw, 66px);
        font-size: clamp(31px, 1.8vw, 40px);
    }

    .mechanism__steps p,
    .outcome div > p:last-child {
        max-width: 380px;
        font-size: clamp(15px, .72vw, 18px);
    }

    .pathway {
        padding: clamp(28px, 1.8vw, 36px) 0;
        font-size: clamp(13px, .72vw, 16px);
    }

    .outcomes {
        margin-top: clamp(104px, 6vw, 142px);
    }

    .outcome h3 {
        font-size: clamp(38px, 2.1vw, 48px);
    }

    .potential h2 {
        max-width: 800px;
        font-size: clamp(56px, 3vw, 76px);
    }

    .contact h2 {
        max-width: 1120px;
        font-size: clamp(84px, 4.2vw, 116px);
    }

    .contact__body {
        grid-template-columns: minmax(0, 1.1fr) minmax(520px, .9fr);
    }

    .contact__signature {
        width: min(44vw, 820px);
    }

    .source-links a,
    .site-footer__legal {
        font-size: clamp(12px, .54vw, 14px);
    }

    .site-footer__copyright {
        font-size: clamp(10px, .48vw, 12px);
    }

    .site-footer__inner {
        min-height: 142px;
    }
}

@keyframes intro-copy {
    from {
        opacity: 0;
        transform: translateY(12px);
    }

    to {
        opacity: 1;
        transform: translateY(0);
    }
}

@keyframes intro-product {
    from {
        opacity: 0;
        transform: translateY(8px) scale(.992);
    }

    to {
        opacity: 1;
        transform: translateY(0) scale(1);
    }
}

@media (min-width: 1181px) and (max-width: 1440px) {
    .hero__grid {
        grid-template-columns: minmax(430px, .9fr) minmax(540px, 1.1fr);
        gap: clamp(40px, 3.8vw, 56px);
    }

    .hero__copy {
        max-width: none;
    }
}

@media (max-width: 1180px) {
    .hero {
        padding-top: calc(var(--header-h) + 52px);
    }

    .hero__grid {
        min-height: 0;
        grid-template-columns: 1fr;
        gap: 62px;
    }

    .hero__copy {
        max-width: 860px;
    }

    h1 {
        font-size: clamp(76px, 9vw, 106px);
    }

    .hero__lead {
        max-width: 720px;
    }

    .product-stage {
        height: clamp(570px, 70vw, 760px);
        min-height: 0;
    }

    .product-stage img {
        width: 100%;
    }

    .mechanism__intro,
    .evidence__intro,
    .potential__body,
    .contact__body {
        grid-template-columns: 1fr;
        gap: 46px;
    }

    .potential__body {
        gap: 32px;
    }

    .mechanism__summary,
    .evidence__intro > p,
    .potential__body p,
    .contact__aside {
        max-width: 690px;
    }

    .mechanism h2,
    .evidence h2,
    .potential h2,
    .contact h2 {
        max-width: 960px;
    }

    .contact__body {
        align-items: start;
    }
}

@media (max-width: 900px) {
    .hero__facts {
        grid-template-columns: 1fr;
    }

    .hero__facts div + div {
        padding-left: 0;
        border-top: 1px solid var(--line);
        border-left: 0;
    }

    .mechanism__steps {
        grid-template-columns: 1fr;
    }

    .mechanism__steps li {
        padding-right: 0;
    }

    .mechanism__steps li + li {
        padding-left: 0;
        border-top: 1px solid var(--line-dark);
        border-left: 0;
    }

    .mechanism__steps h3 {
        margin-top: 40px;
    }

    .outcomes {
        grid-template-columns: 1fr;
    }

    .outcome,
    .outcome + .outcome {
        padding-right: 0;
        padding-left: 0;
        border-left: 0;
    }

    .outcome + .outcome {
        border-top: 1px solid var(--line);
    }

    .evidence__footer {
        flex-direction: column;
    }

    .source-links {
        width: min(100%, 360px);
        align-self: flex-start;
        justify-content: flex-start;
    }
}

@media (max-width: 760px) {
    :root {
        --header-h: 78px;
        --page-x: clamp(20px, 4.5vw, 34px);
    }

    .brand img {
        width: 104px;
    }

    .site-nav__link {
        display: none;
    }

    .site-nav__contacts {
        gap: 6px;
    }

    .site-nav__contact {
        min-height: 38px;
        padding: 0 9px;
        font-size: 11px;
    }

    .hero {
        padding-top: calc(var(--header-h) + 38px);
        padding-bottom: 84px;
    }

    .hero__grid {
        gap: 40px;
    }

    h1 {
        font-size: clamp(52px, 13.6vw, 78px);
    }

    .hero__lead {
        margin-top: 28px;
        font-size: 17px;
        line-height: 1.5;
    }

    .hero__lead + .hero__lead {
        margin-top: 14px;
    }

    .button {
        min-height: 50px;
        padding: 0 17px;
    }

    .product-stage {
        height: clamp(390px, 105vw, 570px);
    }

    .product-stage picture {
        inset: 55px clamp(18px, 6vw, 28px) 57px;
    }

    .product-stage__kicker {
        top: 18px;
        right: 20px;
        left: 20px;
        gap: 16px;
        font-size: 10px;
        letter-spacing: .08em;
    }

    .hero__facts {
        margin-top: 26px;
        grid-template-columns: 1fr;
    }

    .hero__facts div {
        padding: 18px 0 20px;
    }

    .hero__facts div + div {
        padding-left: 0;
        border-top: 1px solid var(--line);
        border-left: 0;
    }

    .hero__facts span,
    .outcome__label,
    .section-label {
        font-size: 10px;
        letter-spacing: .07em;
        line-height: 1.35;
    }

    .hero__facts p,
    .mechanism__steps p,
    .outcome div > p:last-child {
        font-size: 16px;
    }

    .mechanism,
    .evidence,
    .contact {
        padding-top: 92px;
        padding-bottom: 96px;
    }

    .potential {
        padding-top: 72px;
        padding-bottom: 78px;
    }

    .mechanism {
        background-position: center, center, 57% bottom;
        background-size: 100% 100%, 100% 100%, auto 480px;
    }

    .evidence {
        background-position: center, center, 64% bottom;
        background-size: 100% 100%, 100% 100%, auto 600px;
    }

    .section-label {
        margin-bottom: 48px;
        font-size: 10px;
    }

    .mechanism h2,
    .evidence h2,
    .potential h2,
    .contact h2 {
        font-size: clamp(47px, 12vw, 70px);
        letter-spacing: -.052em;
        line-height: 1.02;
    }

    .potential h2 {
        font-size: clamp(34px, 9.5vw, 46px);
        letter-spacing: -.055em;
        line-height: 1.04;
    }

    .mechanism__intro,
    .evidence__intro,
    .potential__body,
    .contact__body {
        gap: 34px;
    }

    .potential__body {
        gap: 26px;
    }

    .mechanism__summary p,
    .evidence__intro > p,
    .potential__body p,
    .contact__aside > p {
        font-size: 17px;
    }

    .potential__body p {
        font-size: 16px;
    }

    .mechanism__steps {
        margin-top: 66px;
        grid-template-columns: 1fr;
    }

    .mechanism__steps li {
        padding: 24px 0 30px;
    }

    .mechanism__steps li + li {
        padding-left: 0;
        border-top: 1px solid var(--line-dark);
        border-left: 0;
    }

    .mechanism__steps h3 {
        margin-top: 34px;
    }

    .pathway {
        display: grid;
        padding: 25px 0;
        justify-items: start;
        gap: 12px;
    }

    .pathway i {
        margin-left: 10px;
        transform: rotate(90deg);
    }

    .outcomes {
        margin-top: 64px;
        grid-template-columns: 1fr;
    }

    .outcome,
    .outcome + .outcome {
        padding: 34px 0 40px;
        border-left: 0;
    }

    .outcome + .outcome {
        border-top: 1px solid var(--line);
    }

    .outcome h3 {
        font-size: 29px;
    }

    .evidence__footer {
        margin-top: 28px;
        flex-direction: column;
    }

    .source-links {
        width: 100%;
        align-self: flex-start;
        flex-direction: column;
        align-items: flex-start;
        justify-content: flex-start;
        gap: 11px;
    }

    .site-footer__legal {
        font-size: 13px;
    }

    .contact__actions {
        display: grid;
        grid-template-columns: 1fr;
    }

    .contact__signature {
        display: none;
    }

    .site-footer__inner {
        min-height: 0;
        padding-top: 34px;
        padding-bottom: 34px;
        grid-template-columns: 1fr;
        align-items: start;
        gap: 24px;
    }

    .site-footer__copyright {
        text-align: left;
    }
}

@media (max-width: 420px) {
    h1 {
        font-size: clamp(49px, 13.2vw, 56px);
    }

    .product-stage figcaption span:last-child {
        text-align: right;
    }

    .outcome {
        grid-template-columns: 42px 1fr;
        gap: 16px;
    }

    .outcome__mark {
        font-size: 11px;
    }
}

@media (max-width: 360px) {
    .mechanism h2,
    .evidence h2,
    .contact h2 {
        font-size: clamp(40px, 13vw, 44px);
    }

    .potential h2 {
        font-size: clamp(32px, 9.5vw, 36px);
        letter-spacing: -.055em;
    }
}

@media (min-width: 761px) and (max-width: 1180px) {
    .product-stage img {
        position: absolute;
        inset: 0;
        width: 100%;
        max-width: none;
        height: 100%;
        max-height: none;
    }
}

@media (orientation: portrait) {
    .mechanism {
        background-image:
            radial-gradient(105% 95% at 0 0, rgba(10, 10, 10, .97) 0%, rgba(10, 10, 10, .83) 48%, rgba(10, 10, 10, .34) 100%),
            linear-gradient(180deg, rgba(10, 10, 10, .995) 0%, rgba(10, 10, 10, .94) 31%, rgba(10, 10, 10, .68) 63%, rgba(10, 10, 10, .46) 100%),
            url("/bimagrumab-assets/mechanism-muscle-hypertrophy-red-v1.png?v=20260901-6");
        background-position: center, center, center bottom;
        background-size: 100% 100%, 100% 100%, min(82vw, 960px) auto;
    }

    .evidence {
        background-image:
            linear-gradient(180deg, rgba(248, 247, 243, .997) 0%, rgba(248, 247, 243, .8) 41%, rgba(248, 247, 243, .16) 66%, rgba(248, 247, 243, 0) 100%),
            radial-gradient(120% 90% at 0 0, rgba(248, 247, 243, .998) 0%, rgba(248, 247, 243, .94) 35%, rgba(248, 247, 243, .42) 58%, rgba(248, 247, 243, .02) 100%),
            url("/bimagrumab-assets/evidence-composition-biological-portrait-v1.png?v=20260901-2");
        background-position: center, center, center bottom;
        background-size: 100% 100%, 100% 100%, min(82vw, 960px) auto;
    }
}

@media (orientation: portrait) and (max-width: 760px) {
    .mechanism {
        background-image:
            radial-gradient(105% 95% at 0 0, rgba(10, 10, 10, .97) 0%, rgba(10, 10, 10, .86) 42%, rgba(10, 10, 10, .45) 76%, rgba(10, 10, 10, .3) 100%),
            linear-gradient(180deg, rgba(10, 10, 10, .995) 0%, rgba(10, 10, 10, .94) 26%, rgba(10, 10, 10, .68) 56%, rgba(10, 10, 10, .38) 100%),
            url("/bimagrumab-assets/mechanism-muscle-hypertrophy-red-v1.png?v=20260901-6");
    }

    .evidence {
        background-image:
            linear-gradient(180deg, rgba(248, 247, 243, .997) 0%, rgba(248, 247, 243, .85) 36%, rgba(248, 247, 243, .4) 64%, rgba(248, 247, 243, .08) 100%),
            radial-gradient(120% 90% at 0 0, rgba(248, 247, 243, .998) 0%, rgba(248, 247, 243, .92) 28%, rgba(248, 247, 243, .6) 50%, rgba(248, 247, 243, .13) 100%),
            url("/bimagrumab-assets/evidence-composition-biological-portrait-v1.png?v=20260901-2");
    }

    .mechanism {
        background-position: center, center, 46% bottom;
        background-size: 100% 100%, 100% 100%, 190% auto;
    }

    .evidence {
        background-position: center, center, center bottom;
        background-size: 100% 100%, 100% 100%, auto 75%;
    }
}

@media (min-width: 761px) and (orientation: landscape) {
    .evidence {
        background-image:
            linear-gradient(180deg, rgba(248, 247, 243, .995) 0%, rgba(248, 247, 243, .72) 42%, rgba(248, 247, 243, .08) 66%, rgba(248, 247, 243, 0) 100%),
            linear-gradient(90deg, rgba(248, 247, 243, .998) 0%, rgba(248, 247, 243, .93) 42%, rgba(248, 247, 243, .04) 76%, rgba(248, 247, 243, 0) 100%),
            url("/bimagrumab-assets/evidence-composition-biological-v1.png?v=20260901-2"),
            url("/bimagrumab-assets/evidence-composition-biological-v1.png?v=20260901-2"),
            url("/bimagrumab-assets/evidence-composition-biological-v1.png?v=20260901-2");
        background-blend-mode: normal, normal, multiply, multiply, normal;
    }
}

@media (max-width: 760px) and (orientation: landscape), (max-height: 500px) and (orientation: landscape) {
    .evidence {
        background-image:
            linear-gradient(180deg, rgba(248, 247, 243, .997) 0%, rgba(248, 247, 243, .85) 36%, rgba(248, 247, 243, .4) 64%, rgba(248, 247, 243, .08) 100%),
            linear-gradient(90deg, rgba(248, 247, 243, .998) 0%, rgba(248, 247, 243, .92) 28%, rgba(248, 247, 243, .6) 50%, rgba(248, 247, 243, .13) 100%),
            url("/bimagrumab-assets/evidence-composition-biological-v1.png?v=20260901-2");
    }
}

@media (prefers-reduced-motion: reduce) {
    html {
        scroll-behavior: auto;
    }

    *,
    *::before,
    *::after {
        animation-duration: .01ms !important;
        animation-iteration-count: 1 !important;
        scroll-behavior: auto !important;
        transition-duration: .01ms !important;
    }
}
